Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ 4-Cyano-3-methylisoquinoline
A potent, cell-permeable, reversible, and specific inhibitor of protein kinase A (IC50 = 30 nM).
MilliporeSigma™ Calbiochem™ HSP70 Activator II, YM-08
A cell-permeable, neutrally charged, pyridinium-to-pyridine substituted YM-01 (Cat
MilliporeSigma™ Calbiochem™ JNK Inhibitor V
The JNK Inhibitor V, also referenced under CAS 345987-15-7, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Psalmotoxin-1
A potent proton-gated sodium channel (ASIC1a) channel blocking neurotoxin (IC50 = 0.9 nM) that can distinguish between the two ASIC1 splice variants, ASIC1a and ASIC1b.
MilliporeSigma™ Calbiochem™ Protein Synthesis Initiation Inhibitor, NSC 119889
The Protein Synthesis Initiation Inhibitor, NSC 119889 blocks 5'-mediated/cap-dependent initiation of protein synthesis. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Calpastatin Peptide
A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC50 = 20 nM for purified rabbit calpain II).
MilliporeSigma™ Calbiochem™ APT1 Inhibitor, palmostatin B
The APT1 Inhibitor, palmostatin B controls the biological activity of APT1.
MilliporeSigma™ Calbiochem™ AAA-ATPase Drg1 Inhibitor, Diazaborine
An anti-bacterial compound that targets NAD(P)H-dependent enoyl acyl carrier protein reductase (ENR) resulting in the inhibition of bacterial fatty acid synthase.
MilliporeSigma™ Calbiochem™ Keap1-Nrf2 Interaction Probe, ML334
A cell-permeable, direct, non-covalent inhibitor of Keap1 - Nrf2 protein - protein interaction (Kd = 1 μM) that causes the dissociation of Nrf2 from keap1 in the cytosol.
MilliporeSigma™ Calbiochem™ KLF5 Inhibitor, CID 5951923
The KLF5 Inhibitor, CID 5951923 controls the biological activity of KLF5.
MilliporeSigma™ Calbiochem™ BRD2 Inhibitor II, BIC1
The BRD2 Inhibitor II, BIC1 controls the biological activity of BRD2.
MilliporeSigma™ Calbiochem™ ALLM
Cell permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM).
MilliporeSigma™ Calbiochem™ Eya2 Phosphatase Inhibitor, MLS000544460
A cell-permeable furylidenebenzohydrazide compound that acts as an inhibitor of Eya2 ED tyrosine phosphatase (IC50
MilliporeSigma™ Calbiochem™ Fas/FasL Antagonist, Kp7-6
The Fas/FasL Antagonist, Kp7-6 controls the biological activity of Fas/FasL. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Apoptosis Activator VII, Apoptozole
The Apoptosis Activator VII, Apoptozole, also referenced under CAS 1054543-47-3, modulates Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.